Bioconjugation is a chemical process that forms a covalent link between two molecules, at least one of which is a biomolecule. This technique has revolutionized various fields, including medicine, diagnostics, and biotechnology.
Application of bioconjugation is pivotal in the development of biopharmaceuticals, including:
- Antibody-Drug Conjugates (ADCs): These combine the targeting capability of antibodies with the potency of cytotoxic drugs, allowing for precise delivery to cancer cells.
- Pegylated Proteins: Attaching polyethylene glycol (PEG) to proteins increases their stability and half-life.
- siRNA Conjugates: Enhance the delivery and efficacy of small interfering RNA (siRNA) therapies.
- Vaccine Conjugates: Improve the immune response by linking antigens to carrier proteins.
Advantages of bioconjugation are:
- Targeted Delivery: Enhances the specificity of drug delivery, reducing side effects and improving therapeutic efficacy.
- Increased Stability: Conjugation can enhance the stability and half-life of therapeutic molecules.
- Versatility: Applicable to a wide range of biomolecules and small molecules, enabling diverse applications in diagnostics and therapeutics.
Amaran Biotech is at the forefront of bioconjugation technology. The company specializes in the development and manufacturing of high-value biopharmaceuticals. Our state-of-the-art facilities and expertise in bioconjugation enhance the ability to produce complex biopharmaceuticals, contributing to advancements in targeted therapies and personalized medicine.